let us deal with this. You have not said whether your aunt and your mother are Christians. You also say you have afflictions of the flesh. There are no big or little sins in God's eyes, so to make your prayers effective, deal with the problem. Repent because the fervent, effective prayer of a righteous man avails much, which is a way of saying if the conditions arn't right, there is a blockage.
Be practical because God expects us to play our part. If life style change is needed as in the case of blood pressure then pray for your mother to be delivered but also recognise that there are very effective medications for high blood pressure and these can buy you time. in the case of cancer, God can do anything but he has set boundries on our time on the Earth so pray for your aunt to know him and put her faith in him.
Now I will pray for each of you joining my faith to yours.